Unlocking the Power of Artificial Intelligence and Big Data in Medicine

Data-driven science and its corollaries in machine learning and the wider field of artificial intelligence have the potential to drive important changes in medicine.
However, medicine is not a science like any other: It is deeply and tightly bound with a large and wide network of legal, ethical, regulatory, economical, and societal dependencies. As a consequence, the scientific and technological progresses in handling information and its further processing and cross-linking for decision support and predictive systems must be accompanied by parallel changes in the global environment, with numerous stakeholders, including citizen and society.
What can be seen at the first glance as a barrier and a mechanism slowing down the progression of data science must, however, be considered an important asset. Only global adoption can transform the potential of big data and artificial intelligence into an effective breakthroughs in handling health and medicine. This requires science and society, scientists and citizens, to progress together.
Most of the daily news and recently published scientific papers on research, innovations, and applications in artificial intelligence (AI) refer to what is known as machine learning—algorithms using massive amounts of data and various methodologies to find patterns, support decisions, make predictions, or, for the deep learning part, self-identify important features in data.
However, AI is a complex concept to grasp, and most people have little understanding of what it really is. AI was founded as an academic discipline in 1956 and, despite its youth, already has a rich history [,]. In more than 60 years of exploration and progress, AI has become a large field of research and development involving multidisciplinary approaches to address many challenges, from theoretical frameworks, methods, and tools to real implementations, risk analysis, and impact measures.
The definition of AI is a moving target and changes over time with the evolution of the field. Since its early days, the field of AI has allowed the development of many techniques supporting decision support and prediction, as it is usually made by humans. As early as 1958, a perceptron was expected to be able “to walk, talk, see, write, reproduce itself and be conscious of its existence,“ which led a large scientific controversy between neural network and symbolic reasoning approaches.
The landscape of AI research includes knowledge representation and engineering; rule-based and symbolic reasoning; temporal reasoning and planning; sensing and perception; learning; evolutionary, emerging, social behaviors; and the ability to move and manipulate objects, to name the most important —deep machine learning with autonomous features extraction.
It is the point of view taken in the paper, acknowledging however that, more recently, there is a trend to restrict AI to the latter, autonomous deep machine learning. As a consequence of the wide landscape, the field draws at large through philosophy, mathematics, information sciences, computer science, psychology, anthropology, social sciences, linguistics, and many others. For some experts and visionary people such as Ray Kurzweil, deep machine learning will allow building of an artificial general intelligence that is able to develop itself autonomously and to have the capacity to understand or learn any intellectual task that a human being can, and even go far beyond the limits of human intelligence, but most experts would agree that there are some big missing pieces and it is still a long way off, despite recent potential important advances in quantic computing.
A recent white paper published by the European Commission and authored by the members of the High-Level Expert Group on AI provides, in a few pages, a good overview on what AI is, its main capabilities, applicable expectations, and disciplines involved.


