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Twist Bioscience, founded in 2013 and headquartered in South San Francisco, California, specializes in synthetic DNA production and next-generation sequencing (NGS) solutions.

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Produces synthetic DNA and next-generation sequencing solutions for biotechnology research.

Twist Bioscience, founded in 2013 and headquartered in South San Francisco, California, specializes in synthetic DNA production and next-generation sequencing (NGS) solutions. The company has carved out a niche in the biotechnology sector, offering DNA synthesis, protein solutions, and NGS applications. Twist Bioscience reported record revenue of $110.7 million in Q2 FY2026, marking a 19% increase year-over-year.

The company’s gross margin improved to 51.6%, driven by efficiencies in its DNA Synthesis and Protein Solutions (DSPS) segment, which grew 28% to $53.3 million. Twist Bioscience serves a diverse customer base, including academic institutions, pharmaceutical companies, and biotech firms, with products shipped to approximately 2,583 customers in Q2 FY2026. The company has raised its revenue guidance for FY2026 to $442-$447 million and anticipates achieving adjusted EBITDA breakeven by Q4 FY2026. Recent strategic moves include a bispecific licensing agreement with Invenra and a partnership with Amazon Web Services for AI-powered drug discovery.

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Who buys this

  • Pharmaceutical companies
  • Biotechnology firms
  • Academic research institutions
  • Clinical diagnostics labs
  • Agricultural biotech companies

Strengths and what to watch

Strengths

  • Strong revenue growth, with 13 consecutive quarters of sequential growth
  • High gross margin of 51.6% in Q2 FY2026
  • Strategic partnerships with Amazon Web Services and Invenra

Watch for

  • Net loss increased to $44.0 million in Q2 FY2026
  • Litigation settlement costs of $7.2 million in Q2 FY2026
  • Dependence on continued growth in DNA synthesis and NGS markets

Recent moves

Key Information

Founded
2013
Headquarters
South San Francisco, California

Frequently Asked Questions

What does Twist Bioscience do?

Twist Bioscience specializes in synthetic DNA production and next-generation sequencing solutions for biotechnology research. The California-based company, founded in 2013, provides DNA synthesis, protein solutions, and NGS applications to pharmaceutical firms, academic institutions, and biotech companies, serving over 2,500 customers globally.

How is Twist Bioscience performing financially in 2026?

Twist Bioscience reported $110.7 million Q2 FY2026 revenue, a 19% year-over-year increase, with gross margins reaching 51.6%. Their DNA Synthesis segment grew 28% to $53.3 million. The company raised full-year guidance to $442-$447 million and anticipates EBITDA breakeven by Q4 FY2026.

Who uses Twist Bioscience's DNA synthesis services?

Twist serves pharmaceutical companies, biotech firms, academic research institutions, clinical diagnostics labs, and agricultural biotech companies. In Q2 FY2026, they shipped products to approximately 2,583 customers, demonstrating broad adoption across the biotechnology research ecosystem for synthetic DNA and sequencing applications.

What are Twist Bioscience's key partnerships?

Twist recently partnered with Amazon Web Services for AI-powered drug discovery and signed a bispecific licensing agreement with Invenra. These collaborations complement their core DNA synthesis business while expanding into computational biology and therapeutic development markets.

What challenges does Twist Bioscience face?

Despite revenue growth, Twist reported a $44 million Q2 FY2026 net loss, including $7.2 million litigation costs. The company depends on continued expansion in competitive DNA synthesis and NGS markets while managing operational costs to achieve projected profitability milestones.

Why choose Twist Bioscience for NGS solutions?

With 13 consecutive quarters of growth and 51.6% gross margins, Twist demonstrates reliable scale in DNA synthesis and sequencing. Their partnerships with AWS and therapeutic developers offer integrated solutions from gene synthesis to AI-driven analysis, particularly valuable for pharmaceutical and institutional researchers.

Sources

  1. investors.twistbioscience.com — Q2 FY2026 financial results and strategic highlights